Tiagabine

Tiagabine is a new generation antiepileptic. This medicine is used in adults and children from 12 years old to treat partial epileptic seizures In other words these are seizures which are not accompanied by altered consciousness. It is prescribed alone or in association with other antiepileptics.

How does tiagabine work?

Like the other antiepileptics (particularly gabapentin), tiagabine acts on the gamma-aminobutyric acid (GABA) receptors. It is intended to increase the activity of the neurotransmitter which is involved in propagation of the nerve impulse.

Do they have contraindications or precautions?

Tiagabine can cause tremor or even abdominal pain. Some patients have also reported headaches.

Sources:

• Merck Manual, 4^th edition
• Institute of pharmaceutical and biological sciences – Lyon faculty of pharmacy.