Glycopeptide

The glycopeptides are a family of antibiotics which have a complex structure and include particularly vancomycin, teicoplanin and ristocetin. These medicines are bactericidal and kill the bacteria they attack. They are administered intravenously or intramuscularly and are particularly used to treat Staphylococcal infections.

How do the glycopeptides work?

The glycopeptides inhibit synthesis of the bacterialcell wall, although they are slow-acting. They are usually administered intravenously. There are however a few oral forms which are prescribed particularly to treat some cases of infectious colitis.

Do they have contraindications or precautions?

Hypersensitivity reactions may occur. These particularly involve skin rashes and episodes of fever. A skin "rash" can be caused if they are infused too quickly. They can also occasionally cause phlebitis with intravenous treatment.

Source: Merck Manual – 4^th editionAfssaps