Antacids

The antacids are calcium, aluminium or magnesium salts used either alone or in combination. They are used to temporarily relieve mild gastro-oesophageal burning sensations. They are generally combined with a topical gastric protective agent.

How do the antacids work?

Antacids are effective to counteract overproduction of hydrochloric acid in the stomach. They neutralise the excess acid because of their basic pH.

Side effects and precautions

The antacids containing aluminium or magnesium salts can cause constipation or diarrhoea. Their main disadvantage is the fact that they can reduce the effectiveness of other medicines. It is therefore essential to leave at least two hours between taking an antacid and another treatment.

Sources:

• Merck Manuel 4th Edition;
• Pharmacorama, website accessed on 5 July 2011;
• Laval University (Canada), website accessed on 5 July 2011.